Abstract Aims Population-wide restrictions during the COVID-19 pandemic may create barriers to mental health diagnosis.This study aims to examine changes in the number of incident cases and the incidence rates of mental health diagnoses during the COVID-19 pandemic.Methods By using electronic health records from France, Germany, Italy, South Korea
Animals have evolved circadian rhythms to adapt to the 24-h day-night cycle.Circadian rhythms are controlled by molecular clocks in the brain and periphery, which is driven by clock genes.The circadian rhythm is propagated from the brain to the periphery by nerves and hormones.Glucocorticoids (GCs) are a class of steroid hormones produced by the In
Background: Adaptive designs and platform designs are among two common clinical trial innovations that are increasingly being used to manage medical intervention portfolios and attain faster regulatory approvals.Planning of adaptive and platform trials necessitate simulations to understand how a set of adaptation rules will likely affect the proper
Recognition plays a key role in the social lives of gregarious species, enabling animals to distinguish among social partners and tailor their behaviour accordingly.As domesticated animals regularly interact with humans, as well as members of their own species, we might expect mechanisms used to discriminate between conspecifics to also apply to hu